Post‐GWAS Polygenic Risk Score: Utility and Challenges

ABSTRACT Over the past decade, through genome‐wide association studies, more than 300 genetic variants have been identified to be associated with either BMD or fracture risk. These genetic variants are common in the general population, but they exert small to modest effects on BMD, suggesting that t...

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Bibliographic Details
Main Authors: Tuan V Nguyen, John A Eisman
Format: Article
Language:English
Published: Wiley 2020-11-01
Series:JBMR Plus
Subjects:
Online Access:https://doi.org/10.1002/jbm4.10411