Acute and Subacute Toxicity In Vivo of Thermal-Sprayed Silver Containing Hydroxyapatite Coating in Rat Tibia

To reduce the incidence of implant-associated infection, we previously developed a novel coating technology using hydroxyapatite (HA) containing silver (Ag). This study examined in vivo acute and subacute toxicity associated with the Ag-HA coating in rat tibiae. Ten-week-old rats received implantati...

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Bibliographic Details
Main Authors: Masatsugu Tsukamoto, Hiroshi Miyamoto, Yoshiki Ando, Iwao Noda, Shuichi Eto, Takayuki Akiyama, Yutaka Yonekura, Motoki Sonohata, Masaaki Mawatari
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/902343