Haemolysis and perturbations in the systemic iron metabolism of suckling, copper-deficient mosaic mutant mice - an animal model of Menkes disease.

The biological interaction between copper and iron is best exemplified by the decreased activity of multicopper ferroxidases under conditions of copper deficiency that limits the availability of iron for erythropoiesis. However, little is known about how copper deficiency affects iron homeostasis th...

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Main Authors: Małgorzata Lenartowicz, Rafał R Starzyński, Wojciech Krzeptowski, Paweł Grzmil, Aleksandra Bednarz, Mateusz Ogórek, Olga Pierzchała, Robert Staroń, Anna Gajowiak, Paweł Lipiński
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4172471?pdf=render