Nobiletin and Xanthohumol Sensitize Colorectal Cancer Stem Cells to Standard Chemotherapy

Nobiletin and Xanthohumol Sensitize Colorectal Cancer Stem Cells to Standard Chemotherapy

Colorectal cancer (CRC) mortality is mainly caused by patient refractoriness to common anti-cancer therapies and consequent metastasis formation. Besides, the notorious toxic side effects of chemotherapy are a concurrent obstacle to be tackled. Thus, new treatment approaches are needed to effectivel...

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Bibliographic Details
Main Authors: Alice Turdo, Antonino Glaviano, Giacomo Pepe, Federica Calapà, Stefania Raimondo, Micol Eleonora Fiori, Daniela Carbone, Manuela Giovanna Basilicata, Veronica Di Sarno, Carmine Ostacolo, Barbara Parrino, Stella Cascioferro, Camilla Pecoraro, Simone Di Franco, Diana Bellavia, Miriam Gaggianesi, Veronica Veschi, Melania Lo Iacono, Gloria Ganduscio, Vincenzo Davide Pantina, Laura Rosa Mangiapane, Maria Rita Bongiorno, Riccardo Alessandro, Matilde Todaro, Ruggero De Maria, Patrizia Diana, Pietro Campiglia, Giorgio Stassi
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
flavonoids
nobiletin
xanthohumol
anti-cancer therapy
cancer stem cells
colorectal cancer
Online Access:https://www.mdpi.com/2072-6694/13/16/3927

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https://www.mdpi.com/2072-6694/13/16/3927

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