Human Fetal Bone Marrow-Derived Mesenchymal Stem Cells Promote the Proliferation and Differentiation of Pancreatic Progenitor Cells and the Engraftment Function of Islet-Like Cell Clusters

Human Fetal Bone Marrow-Derived Mesenchymal Stem Cells Promote the Proliferation and Differentiation of Pancreatic Progenitor Cells and the Engraftment Function of Islet-Like Cell Clusters

Pancreatic progenitor cells (PPCs) are the primary source for all pancreatic cells, including beta-cells, and thus the proliferation and differentiation of PPCs into islet-like cell clusters (ICCs) opens an avenue to providing transplantable islets for diabetic patients. Meanwhile, mesenchymal stem...

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Bibliographic Details
Main Authors: Xing Yu Li, Shang Ying Wu, Po Sing Leung
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:International Journal of Molecular Sciences
Subjects:
diabetes
apoptosis
PI3K
MAPK
co-culture
islet-like cell clusters
co-transplantation
Online Access:https://www.mdpi.com/1422-0067/20/17/4083

Internet

https://www.mdpi.com/1422-0067/20/17/4083

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