Spectrum of genomic variations in Indian patients with progressive familial intrahepatic cholestasis

Spectrum of genomic variations in Indian patients with progressive familial intrahepatic cholestasis

Abstract Background Progressive familial intrahepatic cholestasis (PFIC) is caused by variations in ATP8B1, ABCB11 or ABCB4 genes. Data on genetic variations in Indian patients with PFIC are lacking. Methods Coding and splice regions of the three genes were sequenced in unrelated Indian children wit...

Full description

Bibliographic Details
Main Authors: Anjali Sharma, Ujjal Poddar, Shikha Agnihotry, Shubha R. Phadke, Surender K. Yachha, Rakesh Aggarwal
Format: Article
Language:English
Published: BMC 2018-07-01
Series:BMC Gastroenterology
Subjects:
Progressive familial intrahepatic cholestasis
Hereditary cholestasis
Genetic variation
Polymorphism
Online Access:http://link.springer.com/article/10.1186/s12876-018-0835-6

Internet

http://link.springer.com/article/10.1186/s12876-018-0835-6

Similar Items