Clinical protection from falciparum malaria correlates with neutrophil respiratory bursts induced by merozoites opsonized with human serum antibodies.

Clinical protection from falciparum malaria correlates with neutrophil respiratory bursts induced by merozoites opsonized with human serum antibodies.

BACKGROUND: Effective vaccines to combat malaria are urgently needed, but have proved elusive in the absence of validated correlates of natural immunity. Repeated blood stage infections induce antibodies considered to be the main arbiters of protection from pathology, but their essential functions h...

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Bibliographic Details
Main Authors: Charlotte Joos, Laurence Marrama, Hannah E J Polson, Sandra Corre, Antoine-Marie Diatta, Babacar Diouf, Jean-François Trape, Adama Tall, Shirley Longacre, Ronald Perraut
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2845614?pdf=render

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http://europepmc.org/articles/PMC2845614?pdf=render

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