Cost‐effective purification process development for chimeric hepatitis B core (HBc) virus‐like particles assisted by molecular dynamic simulation

Abstract Inserting foreign epitopes to hepatitis B core (HBc) virus‐like particles (VLPs) could influence the molecular conformation and therefore vary the purification process. In this study, a cost‐effective purification process was developed for two chimeric HBc VLPs displaying Epstein–Barr nucle...

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Bibliographic Details
Main Authors: Bingyang Zhang, Shuang Yin, Yingli Wang, Zhiguo Su, Jingxiu Bi
Format: Article
Language:English
Published: Wiley-VCH 2021-06-01
Series:Engineering in Life Sciences
Subjects:
Online Access:https://doi.org/10.1002/elsc.202000104