Cost‐effective purification process development for chimeric hepatitis B core (HBc) virus‐like particles assisted by molecular dynamic simulation
Abstract Inserting foreign epitopes to hepatitis B core (HBc) virus‐like particles (VLPs) could influence the molecular conformation and therefore vary the purification process. In this study, a cost‐effective purification process was developed for two chimeric HBc VLPs displaying Epstein–Barr nucle...
Main Authors: | Bingyang Zhang, Shuang Yin, Yingli Wang, Zhiguo Su, Jingxiu Bi |
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Format: | Article |
Language: | English |
Published: |
Wiley-VCH
2021-06-01
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Series: | Engineering in Life Sciences |
Subjects: | |
Online Access: | https://doi.org/10.1002/elsc.202000104 |
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