Dose-dependent regulation of horizontal cell fate by Onecut family of transcription factors.

Genome duplication leads to an emergence of gene paralogs that are essentially free to undergo the process of neofunctionalization, subfunctionalization or degeneration (gene loss). Onecut1 (Oc1) and Onecut2 (Oc2) transcription factors, encoded by paralogous genes in mammals, are expressed in precur...

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Bibliographic Details
Main Authors: Michaela Kreplova, Andrea Kuzelova, Barbora Antosova, Lucie Zilova, Herbert Jägle, Zbynek Kozmik
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0237403