In Vitro Differentiation of Neural-Like Cells from Human Embryonic Stem Cells by A Combination of Dorsomorphin, XAV939, and A8301

Objective: Motor neuron differentiation from human embryonic stem cells (hESCs) is a goal of regenerative medicine to provide cell therapy as treatments for diseases that damage motor neurons. Most protocols lack adequate efficiency in generating functional motor neurons. However, small molecules...

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Bibliographic Details
Main Authors: Zahra Valizadeh-Arshad, Ebrahim Shahbazi, Shiva Hashemizadeh, Azadeh Moradmand, Meysam Jangkhah, Sahar Kiani
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2017-11-01
Series:Cell Journal
Subjects:
Online Access:http://celljournal.org/journal/article/16331/download