Partially Defective Store Operated Calcium Entry and Hem(ITAM) Signaling in Platelets of Serotonin Transporter Deficient Mice.

Partially Defective Store Operated Calcium Entry and Hem(ITAM) Signaling in Platelets of Serotonin Transporter Deficient Mice.

Serotonin (5-hydroxytryptamin, 5-HT) is an indolamine platelet agonist, biochemically derived from tryptophan. 5-HT is secreted from the enterochromaffin cells into the gastrointestinal tract and blood. Blood 5-HT has been proposed to regulate hemostasis by acting as a vasoconstrictor and by trigger...

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Main Authors: Karen Wolf, Attila Braun, Elizabeth J Haining, Yu-Lun Tseng, Peter Kraft, Michael K Schuhmann, Sanjeev K Gotru, Wenchun Chen, Heike M Hermanns, Guido Stoll, Klaus-Peter Lesch, Bernhard Nieswandt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4723080?pdf=render

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http://europepmc.org/articles/PMC4723080?pdf=render

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