Comparison of DNA damage in human lymphocytes from healthy individuals and asthma, COPD and lung cancer patients treated in vitro / ex vivo with the bulk nano forms of aspirin and ibuprofen

Comparison of DNA damage in human lymphocytes from healthy individuals and asthma, COPD and lung cancer patients treated in vitro / ex vivo with the bulk nano forms of aspirin and ibuprofen

Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit COX enzyme activity, a significant mechanism of action of NSAIDs. Inflammation is associated with increasing cancer incidence. Recent pre-clinical and clinical studies have shown that NSAID treatment could cause an anti-tumour effect in cancers...

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Bibliographic Details
Main Authors: Mojgan Najafzadeh, Badie Jacobe
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Genetics
Subjects:
Asthma
Ibuprofen
Nanoparticles
COPD
lung cancer
: DNA damage
bulk forms aspirin
Online Access:http://journal.frontiersin.org/Journal/10.3389/conf.fgene.2015.01.00059/full

Internet

http://journal.frontiersin.org/Journal/10.3389/conf.fgene.2015.01.00059/full

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