Determination of lercanidipine in human plasma by an improved UPLC–MS/MS method for a bioequivalence study

Determination of lercanidipine in human plasma by an improved UPLC–MS/MS method for a bioequivalence study

An improved and reliable ultra-performance liquid chromatography/tandem mass spectrometry (UPLC–MS/MS) method has been developed and validated for the determination of lercanidipine in human plasma. Plasma samples with lercanidipine-d3 as an internal standard (IS) were prepared by solid phase extrac...

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Bibliographic Details
Main Authors: Darshan V. Chaudhary, Daxesh P. Patel, Priyanka A. Shah, Jaivik V. Shah, Mallika Sanyal, Pranav S. Shrivastav
Format: Article
Language:English
Published: Elsevier 2016-04-01
Series:Journal of Pharmaceutical Analysis
Subjects:
Lercanidipine
UPLC–MS/MS
Bioequivalence
Solid phase extraction
Human plasma
Online Access:http://www.sciencedirect.com/science/article/pii/S209517791530006X

Internet

http://www.sciencedirect.com/science/article/pii/S209517791530006X

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