Development of a Radiofluorinated Adenosine A<sub>2B</sub> Receptor Antagonist as Potential Ligand for PET Imaging

Development of a Radiofluorinated Adenosine A<sub>2B</sub> Receptor Antagonist as Potential Ligand for PET Imaging

The adenosine A<sub>2B</sub> receptor has been proposed as a novel therapeutic target in cancer, as its expression is drastically elevated in several tumors and cancer cells. Noninvasive molecular imaging via positron emission tomography (PET) would allow the in vivo quantification of th...

Full description

Bibliographic Details
Main Authors: Marcel Lindemann, Rareş-Petru Moldovan, Sonja Hinz, Winnie Deuther-Conrad, Daniel Gündel, Sladjana Dukic-Stefanovic, Magali Toussaint, Rodrigo Teodoro, Cathleen Juhl, Jörg Steinbach, Peter Brust, Christa E. Müller, Barbara Wenzel
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
A<sub>2B</sub> adenosine receptor
adenosine
PET
fluorine-18
metabolism
radiofluorination
Online Access:https://www.mdpi.com/1422-0067/21/9/3197

Internet

https://www.mdpi.com/1422-0067/21/9/3197

Similar Items