The brown adipose tissue glucagon receptor is functional but not essential for control of energy homeostasis in mice

Objective: Administration of glucagon (GCG) or GCG-containing co-agonists reduces body weight and increases energy expenditure. These actions appear to be transduced by multiple direct and indirect GCG receptor (GCGR)-dependent mechanisms. Although the canonical GCGR is expressed in brown adipose ti...

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Bibliographic Details
Main Authors: Jacqueline L. Beaudry, Kiran Deep Kaur, Elodie M. Varin, Laurie L. Baggio, Xiemin Cao, Erin E. Mulvihill, Jennifer H. Stern, Jonathan E. Campbell, Phillip E. Scherer, Daniel J. Drucker
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877819300419