Simultaneous Overexpression of Functional Human HO-1, E5NT and ENTPD1 Protects Murine Fibroblasts against TNF-α-Induced Injury In Vitro.

Simultaneous Overexpression of Functional Human HO-1, E5NT and ENTPD1 Protects Murine Fibroblasts against TNF-α-Induced Injury In Vitro.

Several biomedical applications, such as xenotransplantation, require multiple genes simultaneously expressed in eukaryotic cells. Advances in genetic engineering technologies have led to the development of efficient polycistronic vectors based on the use of the 2A self-processing oligopeptide. The...

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Bibliographic Details
Main Authors: Alessandro Cinti, Marco De Giorgi, Elisa Chisci, Claudia Arena, Gloria Galimberti, Laura Farina, Cristina Bugarin, Ilaria Rivolta, Giuseppe Gaipa, Ryszard Tom Smolenski, Maria Grazia Cerrito, Marialuisa Lavitrano, Roberto Giovannoni
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4626094?pdf=render

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http://europepmc.org/articles/PMC4626094?pdf=render

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