Rational Design of Analyte Channels of the Green Fluorescent Protein for Biosensor Applications

<p>A novel solvent-exposed analyte channel, generated by F165G substitution, on the surface of green fluorescent protein (designated His<sub>6</sub>GFPuv/F165G) was successfully discovered by the aid of molecular modeling software (PyMOL) in conjunction with site-directed mutagenes...

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Bibliographic Details
Main Author: Natta Tansila, Tanawut Tantimongcolwat, Chartchalerm Isarankura-Na-Ayudhya, Chanin Nantasenamat, Virapong Prachayasittikul
Format: Article
Language:English
Published: Ivyspring International Publisher 2007-01-01
Series:International Journal of Biological Sciences
Online Access:http://www.biolsci.org/v03p0463.htm