Synthesis and Antibacterial Properties of New 8-Nitrofluoroquinolone Derivatives

Synthesis and Antibacterial Properties of New 8-Nitrofluoroquinolone Derivatives

The objective of this research was the preparation of new 8-nitrofluoroquinolone models and investigation of their antibacterial properties. The work initially involved large scale preparation of the synthon 7-chloro-1-cyclopropyl-6-fluoro-8-nitro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (3), fo...

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Bibliographic Details
Main Authors: Rana Abu-Dahab, Rula M. Darwish, Ashok K. Shakya, Inas Saleh Al-Mazari, Yusuf M. Al-Hiari
Format: Article
Language:English
Published: MDPI AG 2007-06-01
Series:Molecules
Subjects:
8-Nitrofluoroquinolone Derivatives
Fluoroquinolone
Antibacterial Properties
Online Access:http://www.mdpi.com/1420-3049/12/6/1240/

Internet

http://www.mdpi.com/1420-3049/12/6/1240/

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