The Effect of Grapefruit Juice on the Pharmacokinetics of Tadalafil in Rats

We developed and validated a novel, sensitive, selective, and inexpensive high-performance liquid chromatography (HPLC) method for the determination of tadalafil in rats plasma and to investigate the effect of grapefruit juice on the pharmacokinetics of tadalafil in rats. The ZORBAX Eclipse XDB-C18...

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Bibliographic Details
Main Authors: Xiuwei Shen, Fan Chen, Fengwei Wang, Peng Huang, Wenchao Luo
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2020/1631735