Precision medicine in Parkinson’s disease patients with LRRK2 and GBA risk variants – Let’s get even more personal

Precision medicine in Parkinson’s disease patients with LRRK2 and GBA risk variants – Let’s get even more personal

Abstract Parkinson’s disease (PD) is characterized by motor deficits and a wide variety of non-motor symptoms. The age of onset, rate of disease progression and the precise profile of motor and non-motor symptoms display considerable individual variation. Neuropathologically, the loss of substantia...

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Bibliographic Details
Main Authors: Christian U. von Linstow, Ziv Gan-Or, Patrik Brundin
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Translational Neurodegeneration
Subjects:
Parkinson’s disease
Precision medicine
Personalized medicine
Glucocerebrosidase
GCase
Leucine-rich repeat kinase-2
Online Access:http://link.springer.com/article/10.1186/s40035-020-00218-x

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http://link.springer.com/article/10.1186/s40035-020-00218-x

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