Effects of Theophylline on Chronic Inflammatory Lung Injury Induced by LPS Exposure in Guinea Pigs

Background: Pathogenesis of COPD is, at least in part, attributable to the chronic accumulation of neutrophils in the airways, and morphological changes such as hyperplasia of goblet cells in the airways are often observed in this disease. These structural changes were induced in guinea pigs by repe...

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Bibliographic Details
Main Authors: Yoshio Kaneko, Kazumi Takashima, Naomi Suzuki, Kenjiro Yamana
Format: Article
Language:English
Published: Elsevier 2007-01-01
Series:Allergology International
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893015308947