Novel Perbutyrylated Glucose Derivatives of (–)-Epigallocatechin-3-Gallate Inhibit Cancer Cells Proliferation by Decreasing Phosphorylation of the EGFR: Synthesis, Cytotoxicity, and Molecular Docking

Novel Perbutyrylated Glucose Derivatives of (–)-Epigallocatechin-3-Gallate Inhibit Cancer Cells Proliferation by Decreasing Phosphorylation of the EGFR: Synthesis, Cytotoxicity, and Molecular Docking

Lung cancer is one of the most commonly occurring cancer mortality worldwide. The epidermal growth factor receptor (EGFR) plays an important role in cellular functions and has become the new promising target. Natural products and their derivatives with various structures, unique biological activitie...

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Bibliographic Details
Main Authors: Ya Wang, Xiao-Jing Shen, Fa-Wu Su, Yin-Rong Xie, Li-Xia Wang, Ning Zhang, Yi-Long Wu, Yun Niu, Dong-Ying Zhang, Cheng-Ting Zi, Xuan-Jun Wang, Jun Sheng
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Molecules
Subjects:
EGCG
synthesis
cytotoxicity
EGFR
molecular docking
Online Access:https://www.mdpi.com/1420-3049/26/14/4361

Internet

https://www.mdpi.com/1420-3049/26/14/4361

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