The Microenvironment Is a Critical Regulator of Muscle Stem Cell Activation and Proliferation

Skeletal muscle has a remarkable capacity to regenerate following injury, a property conferred by a resident population of muscle stem cells (MuSCs). In response to injury, MuSCs must double their cellular content to divide, a process requiring significant new biomass in the form of nucleotides, pho...

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Bibliographic Details
Main Authors: John H. Nguyen, Jin D. Chung, Gordon S. Lynch, James G. Ryall
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2019.00254/full