Renal function is associated with blood neurofilament light chain level in older adults

Abstract Neurofilament light chain (NfL) is a novel biomarker of neurodegenerative diseases. It is detectable in the peripheral blood, allowing low-invasive assessment of early signs of neurodegeneration. The level of NfL gradually increases with age; however, what other factors affect it remains un...

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Bibliographic Details
Main Authors: Shoshin Akamine, Noriko Marutani, Daisuke Kanayama, Shiho Gotoh, Riki Maruyama, Kanta Yanagida, Yukako Sakagami, Kohji Mori, Hiroyoshi Adachi, Junji Kozawa, Norikazu Maeda, Michio Otsuki, Takaaki Matsuoka, Hiromi Iwahashi, Iichiro Shimomura, Manabu Ikeda, Takashi Kudo
Format: Article
Language:English
Published: Nature Publishing Group 2020-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-76990-7