Innate and Adaptive Anti-SIV Responses in Macaque Semen: Implications for Infectivity and Risk of Transmission

Innate and Adaptive Anti-SIV Responses in Macaque Semen: Implications for Infectivity and Risk of Transmission

HIV-1 infection is transmitted primarily by sexual exposure, with semen being the principal contaminated fluid. However, HIV-specific immune response in semen has been understudied. We investigated specific parameters of the innate, cellular, and humoral immune response that may affect semen infecti...

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Bibliographic Details
Main Authors: Karunasinee Suphaphiphat, Sibylle Bernard-Stoecklin, Céline Gommet, Benoit Delache, Nathalie Dereuddre-Bosquet, Stephen J. Kent, Bruce D. Wines, P. Mark Hogarth, Roger Le Grand, Mariangela Cavarelli
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Immunology
Subjects:
SIV
cytokines
antibodies
ADCC
CD8+ T cells
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00850/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00850/full

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