Loss of mural cell-derived laminin aggravates hemorrhagic brain injury

Loss of mural cell-derived laminin aggravates hemorrhagic brain injury

Abstract Background Mural cells synthesize and deposit laminin to the basement membrane. To investigate the function of mural cell-derived laminin, we generated a mutant mouse line lacking mural cell-derived laminin (termed PKO). In a previous study, we showed that the PKO mice were grossly normal u...

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Bibliographic Details
Main Authors: Jyoti Gautam, Lingling Xu, Abhijit Nirwane, Benjamin Nguyen, Yao Yao
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Journal of Neuroinflammation
Subjects:
Intracerebral hemorrhage
Blood-brain barrier
Mural cells
Edema
Laminin
Online Access:http://link.springer.com/article/10.1186/s12974-020-01788-3

Internet

http://link.springer.com/article/10.1186/s12974-020-01788-3

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