Suppression of Choroidal Neovascularization by AAV-Based Dual-Acting Antiangiogenic Gene Therapy

Vascular endothelial growth factor A (VEGFA) is involved in the pathogenesis of vasoproliferative retinal diseases, such as exudative age-related macular degeneration (AMD). The objective of this study was to investigate whether dual-acting therapy based on the simultaneous expression of anti-VEGFA...

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Bibliographic Details
Main Authors: Anne Louise Askou, Sidsel Alsing, Josephine N.E. Benckendorff, Andreas Holmgaard, Jacob Giehm Mikkelsen, Lars Aagaard, Toke Bek, Thomas J. Corydon
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:Molecular Therapy: Nucleic Acids
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253119300162