Ceramide synthases expression and role of ceramide synthase-2 in the lung: insight from human lung cells and mouse models.

Increases in ceramide levels have been implicated in the pathogenesis of both acute or chronic lung injury models. However, the role of individual ceramide species, or of the enzymes that are responsible for their synthesis, in lung health and disease has not been clarified. We now show that C24- an...

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Bibliographic Details
Main Authors: Irina Petrache, Krzysztof Kamocki, Christophe Poirier, Yael Pewzner-Jung, Elad L Laviad, Kelly S Schweitzer, Mary Van Demark, Matthew J Justice, Walter C Hubbard, Anthony H Futerman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3653891?pdf=render