Development of Membrane-Bound GM-CSF and IL-18 as an Effective Tumor Vaccine.

Development of Membrane-Bound GM-CSF and IL-18 as an Effective Tumor Vaccine.

The development of effective adjuvant is the key factor to boost the immunogenicity of tumor cells as a tumor vaccine. In this study, we expressed membrane-bound granulocyte-macrophage colony-stimulating factor (GM-CSF) and interleukin-18 (IL-18) as adjuvants in tumor cells to stimulate immune respo...

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Bibliographic Details
Main Authors: Chien-Chiao Huang, Kung-Kai Kuo, Ta-Chun Cheng, Chih-Hung Chuang, Chien-Han Kao, Yuan-Chin Hsieh, Kuang-Hung Cheng, Jaw-Yuan Wang, Chiu-Min Cheng, Chien-Shu Chen, Tian-Lu Cheng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4506079?pdf=render

Internet

http://europepmc.org/articles/PMC4506079?pdf=render

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