Soluble epoxide hydrolase activity determines the severity of ischemia-reperfusion injury in kidney.

Soluble epoxide hydrolase (sEH) in endothelial cells determines the plasma concentrations of epoxyeicosatrienoic acids (EETs), which may act as vasoactive agents to control vascular tone. We hypothesized that the regulation of sEH activity may have a therapeutic value in preventing acute kidney inju...

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Bibliographic Details
Main Authors: Jung Pyo Lee, Seung Hee Yang, Hee-Yoon Lee, Bora Kim, Joo-Youn Cho, Jin Ho Paik, Yun Jung Oh, Dong Ki Kim, Chun Soo Lim, Yon Su Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3349654?pdf=render