Pol α-primase dependent nuclear localization of the mammalian CST complex

Kelich, Papaioannou and Skordalakes investigate the intracellular localization dynamics of the mammalian CST, a protein complex critical for telomere maintenance and homeostasis. They find that the CST complex localizes to the nucleus in a cell cycle-dependent manner that requires binding by Pol α-p...

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Bibliographic Details
Main Authors: Joseph M. Kelich, Harry Papaioannou, Emmanuel Skordalakes
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-01845-4