Biodegradable polymeric microsphere-based drug delivery for inductive browning of fat

Biodegradable polymeric microsphere-based drug delivery for inductive browning of fat

Brown and beige adipocytes are potent therapeutic agents to increase energy expenditure and reduce risks of obesity and its affiliated metabolic symptoms. One strategy to increase beige adipocyte content is through inhibition of the evolutionarily conserved Notch signaling pathway. However, systemic...

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Bibliographic Details
Main Authors: Chunhui eJiang, Liangju eKuang, Madeline P Merkel, Feng eYue, Mario Alberto Cano-Vega, Naagarajan eNarayanan, Shihuan eKuang, Meng eDeng
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Endocrinology
Subjects:
Obesity
microspheres
Drug delivery
PLGA
Browning
Notch inhibition
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2015.00169/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fendo.2015.00169/full

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