Lack of Gαi2 proteins in adipocytes attenuates diet-induced obesity

Lack of Gαi2 proteins in adipocytes attenuates diet-induced obesity

Objectives: Typically, obesity results from an inappropriate balance between energy uptake from nutrient consumption and burning of calories, which leads to a pathological increase in fat mass. Obesity is a major cause of insulin resistance and diabetes. Inhibitory G proteins (Gαi) form a subfamily...

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Bibliographic Details
Main Authors: Veronika Leiss, Annika Schönsiegel, Thorsten Gnad, Johannes Kerner, Jyotsna Kaur, Tina Sartorius, Jürgen Machann, Fritz Schick, Lutz Birnbaumer, Hans-Ulrich Häring, Alexander Pfeifer, Bernd Nürnberg
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Molecular Metabolism
Subjects:
Adipocytes
brown adipose tissue
Gnai2
G proteins
High fat diet
Insulin
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877820301034

Internet

http://www.sciencedirect.com/science/article/pii/S2212877820301034

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