Dafachronic acid and temperature regulate canonical dauer pathways during Nippostrongylus brasiliensis infectious larvae activation

Dafachronic acid and temperature regulate canonical dauer pathways during Nippostrongylus brasiliensis infectious larvae activation

Abstract Background While immune responses to the murine hookworm Nippostrongylus brasiliensis have been investigated, signaling pathways regulating development of infectious larvae (iL3) are not well understood. We hypothesized that N. brasiliensis would use pathways similar to those controlling da...

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Bibliographic Details
Main Authors: Katherine Omueti Ayoade, Faith R. Carranza, Woong Hee Cho, Zhu Wang, Steven A. Kliewer, David J. Mangelsdorf, Jonathan D. C. Stoltzfus
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Parasites & Vectors
Subjects:
Nematode
Hookworm
Dauer
Infectious larva
Dafachronic acid
Insulin signaling
Online Access:http://link.springer.com/article/10.1186/s13071-020-04035-z

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http://link.springer.com/article/10.1186/s13071-020-04035-z

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