Induction of Haemeoxygenase-1 Directly Improves Endothelial Function in Isolated Aortas from Obese Rats through the Ampk-Pi3k/Akt-Enos Pathway

Induction of Haemeoxygenase-1 Directly Improves Endothelial Function in Isolated Aortas from Obese Rats through the Ampk-Pi3k/Akt-Enos Pathway

Background: Induction of haemeoxygenase-1 (HO-1) increases adiponectin secretion by remodeling adipose tissue in obesity. The objective of our study is to explore whether HO-1 induction directly improves endothelial function independent of adiponectin changes in obese rats. Methods: Rats were divide...

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Bibliographic Details
Main Authors: Fang Han, Ying Guo, Lili Xu, Ningning Hou, Fei Han, Xiaodong Sun
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
Haemeoxygenase-1
Free fatty acids
Endothelial dysfunction
Online Access:http://www.karger.com/Article/FullText/430312

Internet

http://www.karger.com/Article/FullText/430312

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