Cloning of Immunogenic Domain of Clostridium Difficile Toxin B in Lactococcus lactis to Develop an Oral Vaccine Based on Lactococcus against Clostridium difficile Associated Colitis

Cloning of Immunogenic Domain of Clostridium Difficile Toxin B in Lactococcus lactis to Develop an Oral Vaccine Based on Lactococcus against Clostridium difficile Associated Colitis

Introduction: Clostridium difficile bacterium is the leading cause of clinical infection and pseudomembranous colitis. Toxin B (TcdB) of C. difficile is regarded as one of the main virulence factors of this bacterium. Moreover, the receptor binding domain (RBD) of this toxin which is known as an imm...

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Bibliographic Details
Main Authors: Yasser Rahimi, Mohammad Rabbani-Khorasgani, Sayyed Hamid Zarkesh-Esfahani, Rahman Emamzadeh, Hossein Keyvani Amineh, Marzieh Rezaei
Format: Article
Language:fas
Published: Ilam University of Medical Sciences 2019-11-01
Series:Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām
Subjects:
clostridium difficile
cloning
toxin b
lactococcus.lactic
Online Access:http://sjimu.medilam.ac.ir/article-1-5207-en.html

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http://sjimu.medilam.ac.ir/article-1-5207-en.html

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