Autophagy Induced by Areca Nut Extract Contributes to Decreasing Cisplatin Toxicity in Oral Squamous Cell Carcinoma Cells: Roles of Reactive Oxygen Species/AMPK Signaling

Autophagy Induced by Areca Nut Extract Contributes to Decreasing Cisplatin Toxicity in Oral Squamous Cell Carcinoma Cells: Roles of Reactive Oxygen Species/AMPK Signaling

Chewing areca nut is closely associated with oral squamous cell carcinoma (OSCC). The current study aimed to investigate potential associations between areca nut extract (ANE) and cisplatin toxicity in OSCC cells. OSCC cells (Cal-27 and Scc-9) viability and apoptosis were analyzed after treatment wi...

Full description

Bibliographic Details
Main Authors: Zhi Xu, Chun-Ming Huang, Zhe Shao, Xiao-Ping Zhao, Meng Wang, Ting-Lin Yan, Xiao-Cheng Zhou, Er-Hui Jiang, Ke Liu, Zheng-Jun Shang
Format: Article
Language:English
Published: MDPI AG 2017-03-01
Series:International Journal of Molecular Sciences
Subjects:
areca nut extracts
reactive oxygen species
AMPK/mTOR signaling
autophagy
oral squamous cell carcinoma
cisplatin
Online Access:http://www.mdpi.com/1422-0067/18/3/524

Internet

http://www.mdpi.com/1422-0067/18/3/524

Similar Items