Vitamin E and selenium administration synergistically mitigates ivermectin and doramectin-induced testicular dysfunction in male Wistar albino rats

Vitamin E and selenium administration synergistically mitigates ivermectin and doramectin-induced testicular dysfunction in male Wistar albino rats

Avermectins are broad-spectrum antiparasitic drugs in veterinary and human medication. The current study aimed to examine the toxic effects of ivermectin (IVM) and doramectin (DRM), with or without co-treatment of vitamin E (Vit.E) and selenium (Se) on apoptosis, oxidative stress and male fertility...

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Bibliographic Details
Main Authors: Ahmed Ezzat Ahmed, Ali Alshehri, M.A. Al-Kahtani, Serag Eldin I. Elbehairi, Mohammed A. Alshehri, Ali A. Shati, Mohammad Y. Alfaifi, Amin A. Al-Doais, Ramadan Taha, Kareem Morsy, Ahmed A. El-Mansi
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Avermectins
Vitamin E
Selenium
Apoptosis
Annexin
PCNA
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220300317

Internet

http://www.sciencedirect.com/science/article/pii/S0753332220300317

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