Neuroprotective Effects of Forced Exercise and Bupropion on Chronic Methamphetamine-induced Cognitive Impairment via Modulation of cAMP Response Element-binding Protein/Brain-derived Neurotrophic Factor Signaling Pathway, Oxidative Stress, and Inflammatory Biomarkers in Rats

Neuroprotective Effects of Forced Exercise and Bupropion on Chronic Methamphetamine-induced Cognitive Impairment via Modulation of cAMP Response Element-binding Protein/Brain-derived Neurotrophic Factor Signaling Pathway, Oxidative Stress, and Inflammatory Biomarkers in Rats

Background: Forced exercise can act as non-pharmacologic neuroprotective agent. In current study, we tried the involved molecular mechanisms of protective effects of forced exercise against methamphetamine induced neurodegeneration. Materials and Methods: Forty adult male rats were divided to Group...

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Bibliographic Details
Main Authors: Parastoo Taheri, Saghar Keshavarzi, Mina Ebadi, Majid Motaghinejad, Manijeh Motevalian
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Advanced Biomedical Research
Subjects:
Cognition impairment
forced exercise
methamphetamine
neurodegeneration
P-CREB/BDNF pathway
Online Access:http://www.advbiores.net/article.asp?issn=2277-9175;year=2018;volume=7;issue=1;spage=151;epage=151;aulast=Taheri

Internet

http://www.advbiores.net/article.asp?issn=2277-9175;year=2018;volume=7;issue=1;spage=151;epage=151;aulast=Taheri

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