Metabolic Regulation of Glycolysis and AMP Activated Protein Kinase Pathways during Black Raspberry-Mediated Oral Cancer Chemoprevention

Metabolic Regulation of Glycolysis and AMP Activated Protein Kinase Pathways during Black Raspberry-Mediated Oral Cancer Chemoprevention

Oral cancer is a public health problem with an incidence of almost 50,000 and a mortality of 10,000 each year in the USA alone. Black raspberries (BRBs) have been shown to inhibit oral carcinogenesis in several preclinical models, but our understanding of how BRB phytochemicals affect the metabolic...

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Bibliographic Details
Main Authors: Thomas J. Knobloch, Nathan M. Ryan, Lei Bruschweiler-Li, Cheng Wang, Matthew C. Bernier, Arpad Somogyi, Pearlly S. Yan, Jessica L. Cooperstone, Xiaokui Mo, Rafael P. Brüschweiler, Christopher M. Weghorst, Steve Oghumu
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Metabolites
Subjects:
HNSCC
metabolomics
transcriptomics
black raspberries
oral cancer
chemoprevention
Online Access:https://www.mdpi.com/2218-1989/9/7/140

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https://www.mdpi.com/2218-1989/9/7/140

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