The Polarity of an Amino Acid at Position 1891 of Severe Fever with Thrombocytopenia Syndrome Virus L Protein Is Critical for the Polymerase Activity

The Polarity of an Amino Acid at Position 1891 of Severe Fever with Thrombocytopenia Syndrome Virus L Protein Is Critical for the Polymerase Activity

Severe fever with thrombocytopenia syndrome virus subclone B7 shows strong plaque formation and cytopathic effect induction compared with other subclones and the parental strain YG1. Compared to YG1 and the other subclones, only B7 possesses a single substitution in the L protein at the amino acid p...

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Bibliographic Details
Main Authors: Kisho Noda, Yoshimi Tsuda, Fumiya Kozawa, Manabu Igarashi, Kenta Shimizu, Jiro Arikawa, Kumiko Yoshimatsu
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Viruses
Subjects:
SFTSV
L protein
bunyavirus
polymerase activity
Online Access:https://www.mdpi.com/1999-4915/13/1/33

Internet

https://www.mdpi.com/1999-4915/13/1/33

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