Tumor-associated carbohydrates and immunomodulatory lectins as targets for cancer immunotherapy

During oncogenesis, tumor cells present specific carbohydrate chains that are new targets for cancer immunotherapy. Whereas these tumor-associated carbohydrates (TACA) can be targeted with antibodies and vaccination approaches, TACA including sialic acid-containing glycans are able to inhibit antica...

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Bibliographic Details
Main Authors: Alfred Zippelius, Heinz Läubli, Natalia Rodrigues Mantuano
Format: Article
Language:English
Published: BMJ Publishing Group 2020-07-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/8/2/e001222.full