Association of polymorphism of CYP2D6 and CYP2C9 genes encoding P-450 proteins of cytochrome with arterial hypertension

Gene polymorphisms of cytochrome P-450 CYP2 encoding proteins of cytochrome P-450 are essential forantihy-pertensive drugs metabolism. Purpose: We study the associations of functionally defective allele variants of CYP2D6 gene and CYP2C9 gene with the degree of arterial hypertension (AH). Materials...

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Bibliographic Details
Main Authors: Saratsev A.V., Posnenkova O.M., Reshetko O.V., Kiselev A.R., Bychkov E.N., Shevchenko O.V., Borodulin V.B., Losev O.E.
Format: Article
Language:Russian
Published: Saratov State Medical University 2012-12-01
Series:Саратовский научно-медицинский журнал
Subjects:
Online Access:http://www.ssmj.ru/system/files/201204-933-937.pdf