Early Embryonic Expression of <i>AP-2α</i> Is Critical for Cardiovascular Development

Early Embryonic Expression of <i>AP-2α</i> Is Critical for Cardiovascular Development

Congenital cardiovascular malformation is a common birth defect incorporating abnormalities of the outflow tract and aortic arch arteries, and mice deficient in the transcription factor <i>AP-2α</i> (<i>Tcfap2a</i>) present with complex defects affecting these structures. AP-...

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Bibliographic Details
Main Authors: Amy-Leigh Johnson, Jürgen E. Schneider, Timothy J. Mohun, Trevor Williams, Shoumo Bhattacharya, Deborah J. Henderson, Helen M. Phillips, Simon D. Bamforth
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
transcription factor AP-2α
cardiovascular development
outflow tract
pharyngeal arch artery
neural crest cell
pharyngeal ectoderm
Online Access:https://www.mdpi.com/2308-3425/7/3/27

Internet

https://www.mdpi.com/2308-3425/7/3/27

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