Production and properties of non-cytotoxic pyomelanin by laccase and comparison to bacterial and synthetic pigments

Abstract Pyomelanin is a polymer of homogentisic acid synthesized by microorganisms. This work aimed to develop a production process and evaluate the quality of the pigment. Three procedures have been elaborated and optimized, (1) an HGA-Mn2+ chemical autoxidation (PyoCHEM yield 0.317 g/g substrate)...

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Bibliographic Details
Main Authors: Faustine Lorquin, Fabio Ziarelli, Agnès Amouric, Carole Di Giorgio, Maxime Robin, Philippe Piccerelle, Jean Lorquin
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-87328-2