The strength of selection is consistent across both domains of the MHC class I peptide-binding groove in birds
Abstract Background The Major Histocompatibility Complex (MHC) codes for the key vertebrate immune receptors responsible for pathogen recognition. Foreign antigens are recognized via their compatibility to hyper-variable region of the peptide-binding groove (PBR), which consists of two separate prot...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-05-01
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Series: | BMC Ecology and Evolution |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12862-021-01812-x |