Bitter taste receptor agonists regulate epithelial two-pore potassium channels via cAMP signaling

Bitter taste receptor agonists regulate epithelial two-pore potassium channels via cAMP signaling

Abstract Background Epithelial solitary chemosensory cell (tuft cell) bitter taste signal transduction occurs through G protein coupled receptors and calcium-dependent signaling pathways. Type II taste cells, which utilize the same bitter taste signal transduction pathways, may also utilize cyclic a...

Full description

Bibliographic Details
Main Authors: Michael A. Kohanski, Lauren Brown, Melissa Orr, Li Hui Tan, Nithin D. Adappa, James N. Palmer, Ronald C. Rubenstein, Noam A. Cohen
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Respiratory Research
Subjects:
Denatonium
Tuft cell
SCC
Antimicrobial peptide
Defensin
Chronic rhinosinusitis
Online Access:https://doi.org/10.1186/s12931-021-01631-0

Internet

https://doi.org/10.1186/s12931-021-01631-0

Similar Items