Type I Interferon Transcriptional Signature in Neutrophils and Low-Density Granulocytes Are Associated with Tissue Damage in Malaria

Type I Interferon Transcriptional Signature in Neutrophils and Low-Density Granulocytes Are Associated with Tissue Damage in Malaria

Neutrophils are the most abundant leukocyte population in the bloodstream, the primary compartment of Plasmodium sp. infection. However, the role of these polymorphonuclear cells in mediating either the resistance or the pathogenesis of malaria is poorly understood. We report that circulating neutro...

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Bibliographic Details
Main Authors: Bruno Coelho Rocha, Pedro Elias Marques, Fabiana Maria de Souza Leoratti, Caroline Junqueira, Dhelio Batista Pereira, Lis Ribeiro do Valle Antonelli, Gustavo Batista Menezes, Douglas Taylor Golenbock, Ricardo Tostes Gazzinelli
Format: Article
Language:English
Published: Elsevier 2015-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715014047

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http://www.sciencedirect.com/science/article/pii/S2211124715014047

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