Type I Interferon Transcriptional Signature in Neutrophils and Low-Density Granulocytes Are Associated with Tissue Damage in Malaria
Neutrophils are the most abundant leukocyte population in the bloodstream, the primary compartment of Plasmodium sp. infection. However, the role of these polymorphonuclear cells in mediating either the resistance or the pathogenesis of malaria is poorly understood. We report that circulating neutro...
Main Authors: | Bruno Coelho Rocha, Pedro Elias Marques, Fabiana Maria de Souza Leoratti, Caroline Junqueira, Dhelio Batista Pereira, Lis Ribeiro do Valle Antonelli, Gustavo Batista Menezes, Douglas Taylor Golenbock, Ricardo Tostes Gazzinelli |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2015-12-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124715014047 |
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